PREPARATION AND CHARACTERIZATION OF SOLID LIPID MICRO/NANOPARTICLES I. EFFECT OF LIPID CONCENTRATION, SURFACTANT TYPE AND CONCENTRATION ON PHYSICAL CHARACTERISTICS OF SOLID LIPID MICRO/NANOPARTICLES
نویسندگان
چکیده
منابع مشابه
Preparation, characterization and evaluation of Ginkgo biloba solid lipid nanoparticles
Objective(s): In this work, Ginkgo biloba extract (GBE) loaded solid lipid nanoparticles (SLNs) were synthesized via high pressure homogenization method and their physicochemical properties, as well as cytotoxicity and antibacterial activities were evaluated.Methods: Ginkgo biloba extract SLNs (GBE-SLNs) were prepared using high pressure homogenization method. The morphology and size of S...
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Nine types of solid lipid nanoparticle (SLN) formulations were produced using tripalmitin (TPM), glyceryl monostearate (GM) or stearic acid (SA), stabilized with lecithin S75 and polysorbate 80. Formulations were prepared presenting PI values within 0.25 to 0.30, and the physicochemical properties, stability upon storage and biocompatibility were evaluated. The average particle size ranged from...
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In order to formulate an efficient and durable mucoadhesive drug delivery system, careful consideration of formulation-related parameters is critical. This study was conducted to investigate the effect of the presence of various types and concentrations of surfactants within or outside Carbopol 934 (C934) as well as hydroxypropylmethyl cellulose (HPMC) solid compacts, on their duration of mucoa...
متن کاملEffect of Surfactant Type and Concentration on the Duration of Mucoadhesion of Carbopol 934 and HPMC Solid Compacts
In order to formulate an efficient and durable mucoadhesive drug delivery system, careful consideration of formulation-related parameters is critical. This study was conducted to investigate the effect of the presence of various types and concentrations of surfactants within or outside Carbopol 934 (C934) as well as hydroxypropylmethyl cellulose (HPMC) solid compacts, on their duration of mucoa...
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ژورنال
عنوان ژورنال: Zagazig Journal of Pharmaceutical Sciences
سال: 2010
ISSN: 2356-9786
DOI: 10.21608/zjps.2010.162481